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Epitope mapping by a Wnt-blocking antibody: evidence of the Wnt binding domain in heparan sulfate
Heparan sulfate (HS) is a polysaccharide known to modulate many important biological processes, including Wnt signaling. However, the biochemical interaction between HS and Wnt molecules is not well characterized largely due to the lack of suitable methods. To determine the Wnt binding domain in HS,...
Autores principales: | Gao, Wei, Xu, Yongmei, Liu, Jian, Ho, Mitchell |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869111/ https://www.ncbi.nlm.nih.gov/pubmed/27185050 http://dx.doi.org/10.1038/srep26245 |
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