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Balancing intestinal and systemic inflammation through cell type-specific expression of the aryl hydrocarbon receptor repressor

As a sensor of polyaromatic chemicals the aryl hydrocarbon receptor (AhR) exerts an important role in immune regulation besides its requirement for xenobiotic metabolism. Transcriptional activation of AhR target genes is counterregulated by the AhR repressor (AhRR) but the exact function of the AhRR...

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Detalles Bibliográficos
Autores principales: Brandstätter, Olga, Schanz, Oliver, Vorac, Julia, König, Jessica, Mori, Tetsushi, Maruyama, Toru, Korkowski, Markus, Haarmann-Stemmann, Thomas, von Smolinski, Dorthe, Schultze, Joachim L., Abel, Josef, Esser, Charlotte, Takeyama, Haruko, Weighardt, Heike, Förster, Irmgard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869119/
https://www.ncbi.nlm.nih.gov/pubmed/27184933
http://dx.doi.org/10.1038/srep26091