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Argonaute-associated short introns are a novel class of gene regulators

MicroRNAs (miRNAs) are short (∼22 nucleotides) regulators of gene expression acting by direct base pairing to 3′-UTR target sites in messenger RNAs. Mature miRNAs are produced by two sequential endonucleolytic cleavages facilitated by Drosha in the nucleus and Dicer in the cytoplasm. A subclass of m...

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Detalles Bibliográficos
Autores principales: Hansen, Thomas B., Venø, Morten T., Jensen, Trine I., Schaefer, Anne, Damgaard, Christian K., Kjems, Jørgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869172/
https://www.ncbi.nlm.nih.gov/pubmed/27173734
http://dx.doi.org/10.1038/ncomms11538