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Norovirus (NoV) specific protective immune responses induced by recombinant P dimer vaccine are enhanced by the mucosal adjuvant FlaB

BACKGROUND: Noroviruses (NoVs) are a major cause of childhood gastroenteritis and foodborne diseases worldwide. Lack of appropriate animal models or cell-based culture systems makes the development and evaluation of NoV-specific vaccines a daunting task. VP1 is the major capsid protein of the NoVs t...

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Detalles Bibliográficos
Autores principales: Verma, Vivek, Tan, Wenzhi, Puth, Sao, Cho, Kyoung-Oh, Lee, Shee Eun, Rhee, Joon Haeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869196/
https://www.ncbi.nlm.nih.gov/pubmed/27184355
http://dx.doi.org/10.1186/s12967-016-0899-4