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Mediator subunit Med12 contributes to the maintenance of neural stem cell identity

BACKGROUND: The RNA polymerase II transcriptional Mediator subunit Med12 is broadly implicated in vertebrate brain development, and genetic variation in human MED12 is associated with X-linked intellectual disability and neuropsychiatric disorders. Although prior studies have begun to elaborate the...

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Detalles Bibliográficos
Autores principales: Kim, Nam Hee, Livi, Carolina B., Yew, P. Renee, Boyer, Thomas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869265/
https://www.ncbi.nlm.nih.gov/pubmed/27188461
http://dx.doi.org/10.1186/s12861-016-0114-0