Selective forces and mutational biases drive stop codon usage in the human genome: a comparison with sense codon usage

BACKGROUND: The three stop codons UAA, UAG, and UGA signal the termination of mRNA translation. As a result of a mechanism that is not adequately understood, they are normally used with unequal frequencies. RESULTS: In this work, we showed that selective forces and mutational biases drive stop codon...

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Detalles Bibliográficos
Autor principal: Trotta, Edoardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869280/
https://www.ncbi.nlm.nih.gov/pubmed/27188984
http://dx.doi.org/10.1186/s12864-016-2692-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869280/
https://www.ncbi.nlm.nih.gov/pubmed/27188984
http://dx.doi.org/10.1186/s12864-016-2692-4

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