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Selective forces and mutational biases drive stop codon usage in the human genome: a comparison with sense codon usage
BACKGROUND: The three stop codons UAA, UAG, and UGA signal the termination of mRNA translation. As a result of a mechanism that is not adequately understood, they are normally used with unequal frequencies. RESULTS: In this work, we showed that selective forces and mutational biases drive stop codon...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869280/ https://www.ncbi.nlm.nih.gov/pubmed/27188984 http://dx.doi.org/10.1186/s12864-016-2692-4 |