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Molecular profile of dissociative drug ketamine in relation to its rapid antidepressant action

BACKGROUND: The NMDA receptor antagonist ketamine was found to act as a fast-acting antidepressant. The effects of single treatment were reported to persist for days to weeks, even in otherwise treatment-refractory cases. Identification of the mechanisms underlying ketamine’s antidepressant action m...

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Detalles Bibliográficos
Autores principales: Ficek, Joanna, Zygmunt, Magdalena, Piechota, Marcin, Hoinkis, Dzesika, Rodriguez Parkitna, Jan, Przewlocki, Ryszard, Korostynski, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869301/
https://www.ncbi.nlm.nih.gov/pubmed/27188165
http://dx.doi.org/10.1186/s12864-016-2713-3