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Glimpse into the future: harnessing autophagy to promote anti-tumor immunity with the DRibbles vaccine

Because the benefits of immune checkpoint blockade may be restricted to tumors with pre-existing immune recognition, novel therapies that facilitate de novo immune activation are needed. DRibbles is a novel multi-valent vaccine that is created by disrupting degradation of intracellular proteins by t...

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Detalles Bibliográficos
Autores principales: Page, David B., Hulett, Tyler W., Hilton, Traci L., Hu, Hong-Ming, Urba, Walter J., Fox, Bernard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869314/
https://www.ncbi.nlm.nih.gov/pubmed/27190627
http://dx.doi.org/10.1186/s40425-016-0130-4