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Single-cell antibody nanowells: a novel technology in detecting anti-SSA/Ro60- and anti-SSB/La autoantibody-producing cells in peripheral blood of rheumatic disease patients

BACKGROUND: Anti-SSA/Ro60 and anti-SSB/La are essential serological biomarkers for rheumatic diseases, specifically Sjögren’s syndrome (SS) and systemic lupus erythematosus (SLE). Currently, laboratory detection technology and platforms are designed with an emphasis on high-throughput methodology; t...

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Detalles Bibliográficos
Autores principales: Esfandiary, Lida, Gupta, Nirupama, Voigt, Alexandria, Wanchoo, Arun, Chan, Edward K. L., Sukumaran, Sukesh, Nguyen, Cuong Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869329/
https://www.ncbi.nlm.nih.gov/pubmed/27184054
http://dx.doi.org/10.1186/s13075-016-1010-5