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Paracoccidioides brasiliensis infection promotes thymic disarrangement and premature egress of mature lymphocytes expressing prohibitive TCRs

BACKGROUND: Paracoccidioidomycosis, a chronic granulomatous fungal disease caused by Paracoccidioides brasiliensis yeast cells affects mainly rural workers, albeit recently cases in immunosuppressed individuals has been reported. Protective immune response against P. brasiliensis is dependent on the...

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Detalles Bibliográficos
Autores principales: Di Gangi, Rosaria, Alves da Costa, Thiago, Thomé, Rodolfo, Peron, Gabriela, Burger, Eva, Verinaud, Liana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869377/
https://www.ncbi.nlm.nih.gov/pubmed/27189089
http://dx.doi.org/10.1186/s12879-016-1561-8