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Paracoccidioides brasiliensis infection promotes thymic disarrangement and premature egress of mature lymphocytes expressing prohibitive TCRs
BACKGROUND: Paracoccidioidomycosis, a chronic granulomatous fungal disease caused by Paracoccidioides brasiliensis yeast cells affects mainly rural workers, albeit recently cases in immunosuppressed individuals has been reported. Protective immune response against P. brasiliensis is dependent on the...
Autores principales: | Di Gangi, Rosaria, Alves da Costa, Thiago, Thomé, Rodolfo, Peron, Gabriela, Burger, Eva, Verinaud, Liana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869377/ https://www.ncbi.nlm.nih.gov/pubmed/27189089 http://dx.doi.org/10.1186/s12879-016-1561-8 |
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