Serial image analysis of Mycobacterium tuberculosis colony growth reveals a persistent subpopulation in sputum during treatment of pulmonary TB

Faster elimination of drug tolerant ‘persister’ bacteria may shorten treatment of tuberculosis (TB) but no method exists to quantify persisters in clinical samples. We used automated image analysis to assess whether studying growth characteristics of individual Mycobacterium tuberculosis colonies fr...

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Detalles Bibliográficos
Autores principales: Barr, David A., Kamdolozi, Mercy, Nishihara, Yo, Ndhlovu, Victor, Khonga, Margaret, Davies, Geraint R., Sloan, Derek J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Churchill Livingstone 2016
Materias:
Drug Discovery and Resistance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869592/
https://www.ncbi.nlm.nih.gov/pubmed/27156626
http://dx.doi.org/10.1016/j.tube.2016.03.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869592/
https://www.ncbi.nlm.nih.gov/pubmed/27156626
http://dx.doi.org/10.1016/j.tube.2016.03.001

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