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Sources and implications of NADH/NAD(+) redox imbalance in diabetes and its complications

NAD(+) is a fundamental molecule in metabolism and redox signaling. In diabetes and its complications, the balance between NADH and NAD(+) can be severely perturbed. On one hand, NADH is overproduced due to influx of hyperglycemia to the glycolytic and Krebs cycle pathways and activation of the poly...

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Detalles Bibliográficos
Autores principales: Wu, Jinzi, Jin, Zhen, Zheng, Hong, Yan, Liang-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869616/
https://www.ncbi.nlm.nih.gov/pubmed/27274295
http://dx.doi.org/10.2147/DMSO.S106087