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Silencing of carboxypeptidase E inhibits cell proliferation, tumorigenicity, and metastasis of osteosarcoma cells

Carboxypeptidase E (CPE), a prohormone processing enzyme, has been implicated in the progression of multiple malignancies. However, the biological role and molecular mechanisms of CPE in osteosarcoma remain elusive. In this study, we assessed the effects of CPE on cell proliferation, tumorigenicity,...

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Detalles Bibliográficos
Autores principales: Fan, Shuli, Li, Xu, Li, Leiming, Wang, Liguo, Du, Zhangzhen, Yang, Yan, Zhao, Jiansong, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869623/
https://www.ncbi.nlm.nih.gov/pubmed/27274275
http://dx.doi.org/10.2147/OTT.S98991