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Silencing of carboxypeptidase E inhibits cell proliferation, tumorigenicity, and metastasis of osteosarcoma cells
Carboxypeptidase E (CPE), a prohormone processing enzyme, has been implicated in the progression of multiple malignancies. However, the biological role and molecular mechanisms of CPE in osteosarcoma remain elusive. In this study, we assessed the effects of CPE on cell proliferation, tumorigenicity,...
Autores principales: | Fan, Shuli, Li, Xu, Li, Leiming, Wang, Liguo, Du, Zhangzhen, Yang, Yan, Zhao, Jiansong, Li, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869623/ https://www.ncbi.nlm.nih.gov/pubmed/27274275 http://dx.doi.org/10.2147/OTT.S98991 |
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