Metformin induces apoptosis of human hepatocellular carcinoma HepG2 cells by activating an AMPK/p53/miR-23a/FOXA1 pathway

The antidiabetic drug metformin has been shown to possess antitumor functions in many types of cancers. Although studies have revealed its beneficial effects on the prognosis of hepatocellular carcinoma (HCC), the detailed molecular mechanism underlying this event remains largely unknown. In this wo...

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Detalles Bibliográficos
Autores principales: Sun, Yunpeng, Tao, Chonglin, Huang, Xiaming, He, Han, Shi, Hongqi, Zhang, Qiyu, Wu, Huanhuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869652/
https://www.ncbi.nlm.nih.gov/pubmed/27274280
http://dx.doi.org/10.2147/OTT.S99770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869652/
https://www.ncbi.nlm.nih.gov/pubmed/27274280
http://dx.doi.org/10.2147/OTT.S99770

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