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Bile duct‐ligated mice exhibit multiple phenotypic similarities to acute decompensation patients despite histological differences
BACKGROUND & AIMS: Patients with decompensated cirrhosis are susceptible to infection. Innate immune dysfunction and development of organ failure are considered to underlie this. A rodent model of liver disease sharing these phenotypic features would assist in vivo study of underlying mechanisms...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869675/ https://www.ncbi.nlm.nih.gov/pubmed/26012885 http://dx.doi.org/10.1111/liv.12876 |