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Bile duct‐ligated mice exhibit multiple phenotypic similarities to acute decompensation patients despite histological differences

BACKGROUND & AIMS: Patients with decompensated cirrhosis are susceptible to infection. Innate immune dysfunction and development of organ failure are considered to underlie this. A rodent model of liver disease sharing these phenotypic features would assist in vivo study of underlying mechanisms...

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Detalles Bibliográficos
Autores principales:	O'Brien, Alastair, China, Louise, Massey, Karen A., Nicolaou, Anna, Winstanley, Alison, Newson, Justine, Hobbs, Adrian, Audzevich, Tatsiana, Gilroy, Derek W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2015
Materias:	Cirrhosis and its Complications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869675/ https://www.ncbi.nlm.nih.gov/pubmed/26012885 http://dx.doi.org/10.1111/liv.12876

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