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Altered ratios of pro‐ and anti‐angiogenic VEGF‐A variants and pericyte expression of DLL4 disrupt vascular maturation in infantile haemangioma

Infantile haemangioma (IH), the most common neoplasm in infants, is a slowly resolving vascular tumour. Vascular endothelial growth factor A (VEGF‐A), which consists of both the pro‐ and anti‐angiogenic variants, contributes to the pathogenesis of IH. However, the roles of different VEGF‐A variants...

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Detalles Bibliográficos
Autores principales: Ye, Xi, Abou‐Rayyah, Yassir, Bischoff, Joyce, Ritchie, Alison, Sebire, Neil J, Watts, Patrick, Churchill, Amanda J, Bates, David O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869683/
https://www.ncbi.nlm.nih.gov/pubmed/26957058
http://dx.doi.org/10.1002/path.4715