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Changes in beta cell function occur in prediabetes and early disease in the Lepr(db) mouse model of diabetes

AIMS/HYPOTHESIS: Type 2 diabetes is a progressive disease that increases morbidity and the risk of premature death. Glucose dysregulation, such as elevated fasting blood glucose, is observed prior to diabetes onset. A decline in beta cell insulin secretion contributes to the later stages of diabetes...

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Detalles Bibliográficos
Autores principales: Do, Oanh H., Gunton, Jenny E., Gaisano, Herbert Y., Thorn, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869737/
https://www.ncbi.nlm.nih.gov/pubmed/27048248
http://dx.doi.org/10.1007/s00125-016-3942-3