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Changes in beta cell function occur in prediabetes and early disease in the Lepr(db) mouse model of diabetes
AIMS/HYPOTHESIS: Type 2 diabetes is a progressive disease that increases morbidity and the risk of premature death. Glucose dysregulation, such as elevated fasting blood glucose, is observed prior to diabetes onset. A decline in beta cell insulin secretion contributes to the later stages of diabetes...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869737/ https://www.ncbi.nlm.nih.gov/pubmed/27048248 http://dx.doi.org/10.1007/s00125-016-3942-3 |