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Role of Dopamine 2 Receptor in Impaired Drug-Cue Extinction in Adolescent Rats

Adolescent drug users display resistance to treatment such as cue exposure therapy (CET), as well as increased liability to relapse. The basis of CET is extinction learning, which involves dopamine signaling in the medial prefrontal cortex (mPFC). This system undergoes dramatic alterations during ad...

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Detalles Bibliográficos
Autores principales: Zbukvic, Isabel C., Ganella, Despina E., Perry, Christina J., Madsen, Heather B., Bye, Christopher R., Lawrence, Andrew J., Kim, Jee Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869820/
https://www.ncbi.nlm.nih.gov/pubmed/26946126
http://dx.doi.org/10.1093/cercor/bhw051