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Suppression of STAT5b in pancreatic cancer cells leads to attenuated gemcitabine chemoresistance, adhesion and invasion

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal solid malignancies, and there is an urgent need for new therapeutic strategies based on the molecular biology of PDAC. Signal transducers and activators of transcription 5 (STAT5) are known to be activated in a variety of malignancies...

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Detalles Bibliográficos
Autores principales: SUMIYOSHI, HIROKI, MATSUSHITA, AKIRA, NAKAMURA, YOSHIHARU, MATSUDA, YOKO, ISHIWATA, TOSHIYUKI, NAITO, ZENYA, UCHIDA, EIJI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869940/
https://www.ncbi.nlm.nih.gov/pubmed/27035235
http://dx.doi.org/10.3892/or.2016.4727