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Arginine Supplementation Recovered the IFN-γ-Mediated Decrease in Milk Protein and Fat Synthesis by Inhibiting the GCN2/eIF2α Pathway, Which Induces Autophagy in Primary Bovine Mammary Epithelial Cells

During the lactation cycle of the bovine mammary gland, autophagy is induced in bovine mammary epithelial cells (BMECs) as a cellular homeostasis and survival mechanism. Interferon gamma (IFN-γ) is an important antiproliferative and apoptogenic factor that has been shown to induce autophagy in multi...

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Detalles Bibliográficos
Autores principales: Xia, Xiaojing, Che, Yanyi, Gao, Yuanyuan, Zhao, Shuang, Ao, Changjin, Yang, Hongjian, Liu, Juxiong, Liu, Guowen, Han, Wenyu, Wang, Yuping, Lei, Liancheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870189/
https://www.ncbi.nlm.nih.gov/pubmed/27025389
http://dx.doi.org/10.14348/molcells.2016.2358