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How should we measure proportionality on relative gene expression data?
Correlation is ubiquitously used in gene expression analysis although its validity as an objective criterion is often questionable. If no normalization reflecting the original mRNA counts in the cells is available, correlation between genes becomes spurious. Yet the need for normalization can be byp...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Berlin Heidelberg
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870310/ https://www.ncbi.nlm.nih.gov/pubmed/26762323 http://dx.doi.org/10.1007/s12064-015-0220-8 |