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Polarizing the Neuron through Sustained Co-expression of Alternatively Spliced Isoforms

Alternative splicing (AS) is an important source of proteome diversity in eukaryotes. However, how this affects protein repertoires at a single-cell level remains an open question. Here, we show that many 3′-terminal exons are persistently co-expressed with their alternatives in mammalian neurons. I...

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Detalles Bibliográficos
Autores principales: Yap, Karen, Xiao, Yixin, Friedman, Brad A., Je, H. Shawn, Makeyev, Eugene V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870516/
https://www.ncbi.nlm.nih.gov/pubmed/27134173
http://dx.doi.org/10.1016/j.celrep.2016.04.012