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Power Calculation of Multi-step Combined Principal Components with Applications to Genetic Association Studies

Principal component analysis (PCA) is a useful tool to identify important linear combination of correlated variables in multivariate analysis and has been applied to detect association between genetic variants and human complex diseases of interest. How to choose adequate number of principal compone...

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Detalles Bibliográficos
Autores principales: Li, Zhengbang, Zhang, Wei, Pan, Dongdong, Li, Qizhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870571/
https://www.ncbi.nlm.nih.gov/pubmed/27189724
http://dx.doi.org/10.1038/srep26243