An intein-mediated modulation of protein stability system and its application to study human cytomegalovirus essential gene function

Functional analysis of the essential proteins encoded by human cytomegalovirus (HCMV) is hindered by the lack of complementing systems. To overcome this difficulty, we have established a novel approach, termed the intein-mediated modulation of protein stability (imPS), in which a destabilizing domai...

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Detalles Bibliográficos
Autores principales: Pan, Deng, Xuan, Baoqin, Sun, Yamei, Huang, Shaowu, Xie, Maorong, Bai, Yadan, Xu, Wenjia, Qian, Zhikang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870628/
https://www.ncbi.nlm.nih.gov/pubmed/27188239
http://dx.doi.org/10.1038/srep26167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870628/
https://www.ncbi.nlm.nih.gov/pubmed/27188239
http://dx.doi.org/10.1038/srep26167

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