Physiological maturation and drug responses of human induced pluripotent stem cell-derived cortical neuronal networks in long-term culture

The functional network of human induced pluripotent stem cell (hiPSC)-derived neurons is a potentially powerful in vitro model for evaluating disease mechanisms and drug responses. However, the culture time required for the full functional maturation of individual neurons and networks is uncertain....

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Detalles Bibliográficos
Autores principales: Odawara, A., Katoh, H., Matsuda, N., Suzuki, I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870631/
https://www.ncbi.nlm.nih.gov/pubmed/27188845
http://dx.doi.org/10.1038/srep26181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870631/
https://www.ncbi.nlm.nih.gov/pubmed/27188845
http://dx.doi.org/10.1038/srep26181

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