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Physiological maturation and drug responses of human induced pluripotent stem cell-derived cortical neuronal networks in long-term culture
The functional network of human induced pluripotent stem cell (hiPSC)-derived neurons is a potentially powerful in vitro model for evaluating disease mechanisms and drug responses. However, the culture time required for the full functional maturation of individual neurons and networks is uncertain....
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870631/ https://www.ncbi.nlm.nih.gov/pubmed/27188845 http://dx.doi.org/10.1038/srep26181 |