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Penfluridol suppresses pancreatic tumor growth by autophagy-mediated apoptosis

Pancreatic tumors exhibit enhanced autophagy as compared to any other cancer, making it resistant to chemotherapy. We evaluated the effect of penfluridol against pancreatic cancer. Penfluridol treatment induced apoptosis and inhibited the growth of Panc-1, BxPC-3 and AsPC-1, pancreatic cancer cells...

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Detalles Bibliográficos
Autores principales: Ranjan, Alok, Srivastava, Sanjay K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870635/
https://www.ncbi.nlm.nih.gov/pubmed/27189859
http://dx.doi.org/10.1038/srep26165