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Ubisol-Q10 Prevents Glutamate-Induced Cell Death by Blocking Mitochondrial Fragmentation and Permeability Transition Pore Opening

Mitochondrial dysfunction and oxidative stress are the major events that lead to the formation of mitochondrial permeability transition pore (mPTP) during glutamate-induced cytotoxicity and cell death. Coenzyme Q10 (CoQ10) has widely been used for the treatment of mitochondrial disorders and neurode...

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Detalles Bibliográficos
Autores principales: Kumari, Santosh, Mehta, Suresh L, Milledge, Gaolin Z., Huang, Xinyu, Li, Haining, Li, P. Andy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870712/
https://www.ncbi.nlm.nih.gov/pubmed/27194946
http://dx.doi.org/10.7150/ijbs.13589