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RNA motif search with data-driven element ordering

BACKGROUND: In this paper, we study the problem of RNA motif search in long genomic sequences. This approach uses a combination of sequence and structure constraints to uncover new distant homologs of known functional RNAs. The problem is NP-hard and is traditionally solved by backtracking algorithm...

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Detalles Bibliográficos
Autores principales: Rampášek, Ladislav, Jimenez, Randi M., Lupták, Andrej, Vinař, Tomáš, Brejová, Broňa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870747/
https://www.ncbi.nlm.nih.gov/pubmed/27188396
http://dx.doi.org/10.1186/s12859-016-1074-x