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V-akt murine thymoma viral oncogene homolog 3 (AKT3) contributes to poor disease outcome in humans and mice with pneumococcal meningitis

Pneumococcal meningitis is the most common and severe form of bacterial meningitis. Fatality rates are substantial, and long-term sequelae develop in about half of survivors. Here, we have performed a prospective nationwide genetic association study using the Human Exome BeadChip and identified gene...

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Detalles Bibliográficos
Autores principales: Valls Serón, Mercedes, Ferwerda, Bart, Engelen-Lee, JooYeon, Geldhoff, Madelijn, Jaspers, Valery, Zwinderman, Aeilko H., Tanck, Michael W., Baas, Frank, van der Ende, Arie, Brouwer, Matthijs C., van de Beek, Diederik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870776/
https://www.ncbi.nlm.nih.gov/pubmed/27193124
http://dx.doi.org/10.1186/s40478-016-0320-9