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Aromatase Inhibition Reduces Insulin Sensitivity in Healthy Men

CONTEXT: Deficiency of aromatase, the enzyme that catalyzes the conversion of androgens to estrogens, is associated with insulin resistance in humans and mice. OBJECTIVE: We hypothesized that pharmacological aromatase inhibition results in peripheral insulin resistance in humans. DESIGN: This was a...

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Detalles Bibliográficos
Autores principales: Gibb, Fraser W., Homer, Natalie Z. M., Faqehi, Abdullah M. M., Upreti, Rita, Livingstone, Dawn E., McInnes, Kerry J., Andrew, Ruth, Walker, Brian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870856/
https://www.ncbi.nlm.nih.gov/pubmed/26967690
http://dx.doi.org/10.1210/jc.2015-4146