Cargando…

Aromatase Inhibition Reduces Insulin Sensitivity in Healthy Men

CONTEXT: Deficiency of aromatase, the enzyme that catalyzes the conversion of androgens to estrogens, is associated with insulin resistance in humans and mice. OBJECTIVE: We hypothesized that pharmacological aromatase inhibition results in peripheral insulin resistance in humans. DESIGN: This was a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gibb, Fraser W., Homer, Natalie Z. M., Faqehi, Abdullah M. M., Upreti, Rita, Livingstone, Dawn E., McInnes, Kerry J., Andrew, Ruth, Walker, Brian R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Endocrine Society 2016
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870856/ https://www.ncbi.nlm.nih.gov/pubmed/26967690 http://dx.doi.org/10.1210/jc.2015-4146

Ejemplares similares

Higher Insulin Resistance and Adiposity in Postmenopausal Women With Breast Cancer Treated With Aromatase Inhibitors
por: Gibb, Fraser W, et al.
Publicado: (2019)

Derivatization of estrogens enhances specificity and sensitivity of analysis of human plasma and serum by liquid chromatography tandem mass spectrometry
por: Faqehi, Abdullah M.M., et al.
Publicado: (2016)

Derivatization with 2-hydrazino-1-methylpyridine enhances sensitivity of analysis of 5α-dihydrotestosterone in human plasma by liquid chromatography tandem mass spectrometry
por: Faqehi, Abdullah MM, et al.
Publicado: (2021)

5α-Reductase Type 1 Modulates Insulin Sensitivity in Men
por: Upreti, Rita, et al.
Publicado: (2014)

Simultaneous pharmacokinetic and pharmacodynamic analysis of 5α-reductase inhibitors and androgens by liquid chromatography tandem mass spectrometry
por: Upreti, Rita, et al.
Publicado: (2015)

MON-118 Biochemical and Clinical Correlates of Subcutaneous Adipose mRNA Transcript Levels in Men with T2DM
por: Tun, Nyo Nyo, et al.
Publicado: (2019)

Aromatase Activity and Bone Loss in Men
por: Merlotti, Daniela, et al.
Publicado: (2011)

Metformin Increases Cortisol Regeneration by 11βHSD1 in Obese Men With and Without Type 2 Diabetes Mellitus
por: Anderson, Anna J., et al.
Publicado: (2016)

Aromatase inhibitors in men: effects and therapeutic options
por: de Ronde, Willem, et al.
Publicado: (2011)

Effects of Obesity and Insulin on Tissue-Specific Recycling Between Cortisol and Cortisone in Men
por: Anderson, Anna J, et al.
Publicado: (2020)

Sleep Restriction for 1 Week Reduces Insulin Sensitivity in Healthy Men
por: Buxton, Orfeu M., et al.
Publicado: (2010)

Measurement of tamsulosin in human serum by liquid chromatography–tandem mass spectrometry()
por: Upreti, Rita, et al.
Publicado: (2013)

Aromatase in the Human Brain
por: Azcoitia, Iñigo, et al.
Publicado: (2021)

Endocrine Determinants of Changes in Insulin Sensitivity and Insulin Secretion during a Weight Cycle in Healthy Men
por: Karschin, Judith, et al.
Publicado: (2015)

Antitumor activity of Z-endoxifen in aromatase inhibitor-sensitive and aromatase inhibitor-resistant estrogen receptor-positive breast cancer
por: Jayaraman, Swaathi, et al.
Publicado: (2020)

Aromatase and Dual Aromatase-Steroid Sulfatase Inhibitors from the Letrozole and Vorozole Templates
por: Wood, Paul M, et al.
Publicado: (2011)

Long-Term Effect of Aromatase Inhibition in Aromatase Excess Syndrome
por: Binder, Gerhard, et al.
Publicado: (2021)

Review of the Literature on Ocular Complications Associated With Aromatase Inhibitor Use
por: Almafreji, Ibrahim, et al.
Publicado: (2021)

Salicylate Downregulates 11β-HSD1 Expression in Adipose Tissue in Obese Mice and in Humans, Mediating Insulin Sensitization
por: Nixon, Mark, et al.
Publicado: (2012)

The Utilization and Impact of Aromatase Inhibitor Therapy in Men With Elevated Estradiol Levels on Testosterone Therapy
por: Punjani, Nahid, et al.
Publicado: (2021)

A Case of Erythrocytosis in a Patient Treated with an Aromatase Inhibitor for Breast Cancer
por: Iyengar, Abhinav, et al.
Publicado: (2013)

Sequencing of aromatase inhibitors
por: Bertelli, G
Publicado: (2005)

Modulation of Aromatase by Phytoestrogens
por: Lephart, Edwin D.
Publicado: (2015)

Epitope Characterization of an Aromatase Monoclonal Antibody Suitable for the Assessment of Intratumoral Aromatase Activity
por: Hong, Yanyan, et al.
Publicado: (2009)

Deletion of the Androgen Receptor in Adipose Tissue in Male Mice Elevates Retinol Binding Protein 4 and Reveals Independent Effects on Visceral Fat Mass and on Glucose Homeostasis
por: McInnes, Kerry J., et al.
Publicado: (2012)

Educational outreach visits to improve venous thromboembolism prevention in hospitalised medical patients: a prospective before-and-after intervention study
por: Duff, Jed, et al.
Publicado: (2013)

Predictors of Pain Reduction in Trials of Interventions for Aromatase Inhibitor–Associated Musculoskeletal Symptoms
por: Henry, N Lynn, et al.
Publicado: (2021)

Effects of steroidal and nonsteroidal aromatase inhibitors on markers of bone turnover in healthy postmenopausal women
por: Goss, Paul E, et al.
Publicado: (2007)

Intranasal Insulin Enhances Postprandial Thermogenesis and Lowers Postprandial Serum Insulin Levels in Healthy Men
por: Benedict, Christian, et al.
Publicado: (2011)

Correlates of insulin clearance in apparently healthy non-obese Japanese men
por: Kaga, Hideyoshi, et al.
Publicado: (2017)

Differential dendritic cell expression in chronic inflammatory arthritis: implications for their maturation, recruitment and involvement in disease
por: Jongbloed, S, et al.
Publicado: (2004)

Aromatase inhibitors in post-menopausal endometriosis
por: Polyzos, Nikolaos P, et al.
Publicado: (2011)

Bone Health History in Breast Cancer Patients on Aromatase Inhibitors
por: Kwan, Marilyn L., et al.
Publicado: (2014)

Bone loss and the aromatase inhibitors
por: Lester, J, et al.
Publicado: (2005)

Aromatase inhibitors in male sex
por: Singh, Santosh Kumar
Publicado: (2013)

Aromatase inhibitors in the treatment of endometriosis
por: Słopień, Radosław, et al.
Publicado: (2016)

Molecular Docking of Aromatase Inhibitors
por: Suvannang, Naravut, et al.
Publicado: (2011)

Aromatase Inhibitors in Erectile Dysfunction
por: Singh, Santosh
Publicado: (2021)

Liver Enzymes Are Associated With Hepatic Insulin Resistance, Insulin Secretion, and Glucagon Concentration in Healthy Men and Women
por: Bonnet, Fabrice, et al.
Publicado: (2011)

Molecular response to aromatase inhibitor treatment in primary breast cancer
por: Mackay, Alan, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_kjf537sqt1foqfskd27pm8oov6