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Crystal Structure of Hyp-1, a Hypericum perforatum PR-10 Protein, in Complex with Melatonin

Hyp-1, a PR-10-fold protein from Hypericum perforatum, was crystallized in complex with melatonin (MEL). The structure confirms the conserved protein fold and the presence of three unusual ligand binding sites, two of which are internal chambers (1,2), while the third one (3) is formed as an invagin...

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Detalles Bibliográficos
Autores principales: Sliwiak, Joanna, Dauter, Zbigniew, Jaskolski, Mariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870859/
https://www.ncbi.nlm.nih.gov/pubmed/27242869
http://dx.doi.org/10.3389/fpls.2016.00668