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Multiple Transduction Pathways Mediate Thyrotropin Receptor Signaling in Preosteoblast-Like Cells

It has been shown that the TSH receptor (TSHR) couples to a number of different signaling pathways, although the Gs-cAMP pathway has been considered primary. Here, we measured the effects of TSH on bone marker mRNA and protein expression in preosteoblast-like U2OS cells stably expressing TSHRs. We d...

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Detalles Bibliográficos
Autores principales: Boutin, Alisa, Neumann, Susanne, Gershengorn, Marvin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870888/
https://www.ncbi.nlm.nih.gov/pubmed/26950201
http://dx.doi.org/10.1210/en.2015-2040