Affinity regression predicts the recognition code of nucleic acid binding proteins

Predicting the affinity profiles of nucleic acid-binding proteins directly from the protein sequence is a major unsolved problem. We present a statistical approach for learning the recognition code of a family of transcription factors (TFs) or RNA-binding proteins (RBPs) from high-throughput binding...

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Detalles Bibliográficos
Autores principales: Pelossof, Raphael, Singh, Irtisha, Yang, Julie L., Weirauch, Matthew T., Hughes, Timothy R., Leslie, Christina S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871164/
https://www.ncbi.nlm.nih.gov/pubmed/26571099
http://dx.doi.org/10.1038/nbt.3343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871164/
https://www.ncbi.nlm.nih.gov/pubmed/26571099
http://dx.doi.org/10.1038/nbt.3343

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