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Depolarization of sperm membrane potential is a common feature of men with subfertility and is associated with low fertilization rate at IVF

STUDY QUESTION: Are significant abnormalities in outward (K(+)) conductance and resting membrane potential (V(m)) present in the spermatozoa of patients undertaking IVF and ICSI and if so, what is their functional effect on fertilization success? SUMMARY ANSWER: Negligible outward conductance (≈5% o...

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Detalles Bibliográficos
Autores principales: Brown, Sean G., Publicover, Stephen J., Mansell, Steven A., Lishko, Polina V., Williams, Hannah L., Ramalingam, Mythili, Wilson, Stuart M., Barratt, Christopher L.R., Sutton, Keith A., Da Silva, Sarah Martins
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871192/
https://www.ncbi.nlm.nih.gov/pubmed/27052499
http://dx.doi.org/10.1093/humrep/dew056