Cargando…
Depolarization of sperm membrane potential is a common feature of men with subfertility and is associated with low fertilization rate at IVF
STUDY QUESTION: Are significant abnormalities in outward (K(+)) conductance and resting membrane potential (V(m)) present in the spermatozoa of patients undertaking IVF and ICSI and if so, what is their functional effect on fertilization success? SUMMARY ANSWER: Negligible outward conductance (≈5% o...
Autores principales: | Brown, Sean G., Publicover, Stephen J., Mansell, Steven A., Lishko, Polina V., Williams, Hannah L., Ramalingam, Mythili, Wilson, Stuart M., Barratt, Christopher L.R., Sutton, Keith A., Da Silva, Sarah Martins |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871192/ https://www.ncbi.nlm.nih.gov/pubmed/27052499 http://dx.doi.org/10.1093/humrep/dew056 |
Ejemplares similares
-
Specific loss of CatSper function is sufficient to compromise fertilizing capacity of human spermatozoa
por: Williams, Hannah L., et al.
Publicado: (2015) -
Single-cell analysis of [Ca(2+)](i) signalling in sub-fertile men: characteristics and relation to fertilization outcome
por: Kelly, Mark C, et al.
Publicado: (2018) -
p,p′-DDE activates CatSper and compromises human sperm function at environmentally relevant concentrations
por: Tavares, Renata S., et al.
Publicado: (2013) -
Sperm selection in natural conception: what can we learn from Mother Nature to improve assisted reproduction outcomes?
por: Sakkas, Denny, et al.
Publicado: (2015) -
Human sperm ion channel (dys)function: implications for fertilization
por: Brown, Sean G, et al.
Publicado: (2019)