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Gaining power and precision by using model–based weights in the analysis of late stage cancer trials with substantial treatment switching
In randomised controlled trials of treatments for late‐stage cancer, it is common for control arm patients to receive the experimental treatment around the point of disease progression. This treatment switching can dilute the estimated treatment effect on overall survival and impact the assessment o...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871231/ https://www.ncbi.nlm.nih.gov/pubmed/26576494 http://dx.doi.org/10.1002/sim.6801 |