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Doxorubicin induced heart failure: Phenotype and molecular mechanisms
Long term survival of childhood cancers is now more than 70%. Anthracyclines, including doxorubicin, are some of the most efficacious anticancer drugs available. However, its use as a chemotherapeutic agent is severely hindered by its dose-limiting toxicities. Most notably observed is cardiotoxicity...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871279/ https://www.ncbi.nlm.nih.gov/pubmed/27213178 http://dx.doi.org/10.1016/j.ijcha.2015.11.004 |