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Doxorubicin induced heart failure: Phenotype and molecular mechanisms

Long term survival of childhood cancers is now more than 70%. Anthracyclines, including doxorubicin, are some of the most efficacious anticancer drugs available. However, its use as a chemotherapeutic agent is severely hindered by its dose-limiting toxicities. Most notably observed is cardiotoxicity...

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Detalles Bibliográficos
Autores principales: Mitry, Maria A., Edwards, John G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871279/
https://www.ncbi.nlm.nih.gov/pubmed/27213178
http://dx.doi.org/10.1016/j.ijcha.2015.11.004