A Molecular Mechanism to Regulate Lysosome Motility for Lysosome Positioning and Tubulation

To mediate the degradation of bio-macromolecules, lysosomes must traffic towards cargo-carrying vesicles for subsequent membrane fusion or fission. Mutations of the lysosomal Ca(2+) channel TRPML1 cause lysosome storage disease (LSD) characterized by disordered lysosomal membrane trafficking in cell...

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Detalles Bibliográficos
Autores principales: Li, Xinran, Rydzewski, Nicholas, Hider, Ahmad, Zhang, Xiaoli, Yang, Junsheng, Wang, Wuyang, Gao, Qiong, Cheng, Xiping, Xu, Haoxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871318/
https://www.ncbi.nlm.nih.gov/pubmed/26950892
http://dx.doi.org/10.1038/ncb3324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871318/
https://www.ncbi.nlm.nih.gov/pubmed/26950892
http://dx.doi.org/10.1038/ncb3324

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