LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor

Mostrar otras versiones (1)

The bromodomain‐containing proteins BRD9 and BRD7 are part of the human SWI/SNF chromatin‐remodeling complexes BAF and PBAF. To date, no selective inhibitor for BRD7/9 has been reported despite its potential value as a biological tool or as a lead for future therapeutics. The quinolone‐fused lactam...

Descripción completa

Detalles Bibliográficos
Autores principales: Clark, Peter G. K., Vieira, Lucas C. C., Tallant, Cynthia, Fedorov, Oleg, Singleton, Dean C., Rogers, Catherine M., Monteiro, Octovia P., Bennett, James M., Baronio, Roberta, Müller, Susanne, Daniels, Danette L., Méndez, Jacqui, Knapp, Stefan, Brennan, Paul E., Dixon, Darren J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY‐VCH Verlag 2015
Materias:
Zuschriften
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871321/
https://www.ncbi.nlm.nih.gov/pubmed/27346896
http://dx.doi.org/10.1002/ange.201501394

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871321/
https://www.ncbi.nlm.nih.gov/pubmed/27346896
http://dx.doi.org/10.1002/ange.201501394

Ejemplares similares