Powerful Complex Immunoadjuvant Based on Synergistic Effect of Combined TLR4 and NOD2 Activation Significantly Enhances Magnitude of Humoral and Cellular Adaptive Immune Responses

Binding of pattern recognition receptors (PRRs) by pathogen-associated molecular patterns (PAMPs) activates innate immune responses and contributes to development of adaptive immunity. Simultaneous stimulation of different types of PRRs can have synergistic immunostimulatory effects resulting in enh...

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Detalles Bibliográficos
Autores principales: Tukhvatulin, Amir I., Dzharullaeva, Alina S., Tukhvatulina, Natalia M., Shcheblyakov, Dmitry V., Shmarov, Maxim M., Dolzhikova, Inna V., Stanhope-Baker, Patricia, Naroditsky, Boris S., Gudkov, Andrei V., Logunov, Denis Y., Gintsburg, Alexander L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871337/
https://www.ncbi.nlm.nih.gov/pubmed/27187797
http://dx.doi.org/10.1371/journal.pone.0155650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871337/
https://www.ncbi.nlm.nih.gov/pubmed/27187797
http://dx.doi.org/10.1371/journal.pone.0155650

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