Anti-TGF-β Antibody, 1D11, Ameliorates Glomerular Fibrosis in Mouse Models after the Onset of Proteinuria

Fibrosis is a final common pathway leading to loss of kidney function, in which the fibrogenic cytokine, transforming growth factor β (TGF-β), plays a central role. While previous studies showed that TGF-β antagonism by various means prevents fibrosis in mouse models, clinical approaches based on th...

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Detalles Bibliográficos
Autores principales: Liang, Xiaoyan, Schnaper, H. William, Matsusaka, Taiji, Pastan, Ira, Ledbetter, Steve, Hayashida, Tomoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871338/
https://www.ncbi.nlm.nih.gov/pubmed/27187580
http://dx.doi.org/10.1371/journal.pone.0155534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871338/
https://www.ncbi.nlm.nih.gov/pubmed/27187580
http://dx.doi.org/10.1371/journal.pone.0155534

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