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PD-1/CTLA-4 Blockade Inhibits Epstein-Barr Virus-Induced Lymphoma Growth in a Cord Blood Humanized-Mouse Model

Epstein-Barr virus (EBV) infection causes B cell lymphomas in humanized mouse models and contributes to a variety of different types of human lymphomas. T cells directed against viral antigens play a critical role in controlling EBV infection, and EBV-positive lymphomas are particularly common in im...

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Detalles Bibliográficos
Autores principales: Ma, Shi-Dong, Xu, Xuequn, Jones, Richard, Delecluse, Henri-Jacques, Zumwalde, Nicholas A., Sharma, Akshat, Gumperz, Jenny E., Kenney, Shannon C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871349/
https://www.ncbi.nlm.nih.gov/pubmed/27186886
http://dx.doi.org/10.1371/journal.ppat.1005642