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Molecular Mechanisms of Malignant Transformation by Low Dose Cadmium in Normal Human Bronchial Epithelial Cells

Cadmium is a carcinogenic metal, the mechanisms of which are not fully understood. In this study, human bronchial epithelial cells were transformed with sub-toxic doses of cadmium (0.01, 0.05, and 0.1 μM) and transformed clones were characterized for gene expression changes using RNA-seq, as well as...

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Detalles Bibliográficos
Autores principales: Cartularo, Laura, Kluz, Thomas, Cohen, Lisa, Shen, Steven S., Costa, Max
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871351/
https://www.ncbi.nlm.nih.gov/pubmed/27186882
http://dx.doi.org/10.1371/journal.pone.0155002